China (Mainland)
Diltiazem Hydrochloride CAS NO.33286-22-5
- Min.Order: 10 Gram
- Payment Terms: L/C,D/A,D/P,T/T,
- Product Details
Keywords
- Cardizem 33286-22-5
- Diltiazem Hydrochloride
- Diltiazem HCl
Quick Details
- ProName: Diltiazem Hydrochloride
- CasNo: 33286-22-5
- Molecular Formula: C22H27ClN2O4S
- Appearance: white or almost white, crystalline pow...
- Application: Calcium channel blocker
- DeliveryTime: within 7 days after order confirmation
- PackAge: 1kg/package, 25kg/bag, 25kg/drum
- Port: Shanghai, Qingdao, Tianjin, Ningbo, Xi...
- ProductionCapacity: Metric Ton/Day
- Purity: 99%+
- Storage: store in cool and dry place, keep away...
- Transportation: By air, by courier, by sea
- LimitNum: 10 Gram
- Residue on Ignition: Maximum 0.1%
- Heavy Metal: Maximum 10ppm
Superiority
XI'AN VEDA CHEMICAL CO.,LTD(VEDACHEM), is specializes in
APIs and Intermediates.
Diltiazem Hydrochloride is one of the featured products.
Diltiazem is the generic form of the brand-name drug Cardizem, which is
used to treat high blood pressure and control chest pain (known as angina).
It's also sometimes used to treat abnormal heart rhythms (arrhythmia).
There are several other brand names of this medication, including Cartia,
Dilacor XR, Diltzac, Taztia and Tiazac.
Details
|
product Name |
Diltiazem HCl |
|
Synonyms |
Diltiazem Hydrochloride; (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate; (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride (1:1); Dilthiazem hydrochloride |
|
Molecular Formula |
C22H27ClN2O4S |
|
Molecular Weight |
450.9788 |
|
InChI |
InChI=1/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1 |
|
CAS Registry Number |
33286-22-5 |
|
EINECS |
251-443-3 |
|
Molecular Structure |
|
|
Melting point |
210-215℃ |
|
Boiling point |
594.4°C at 760 mmHg |
|
Flash point |
313.3°C |
|
Water solubility |
soluble |
|
Vapour Pressur |
4.27E-14mmHg at 25°C |
|
Hazard Symbols |
|
|
Risk Codes |
R22:; |
|
Safety Description |
S36/37:; |
Xn:Harmful;
|
Appearance |
White or almost white, crystalline powder. |
|
|
Solubility |
Freely soluble in water, in methanol and in methylene chloride, slightly soluble in anhydrous ethanol. |
|
|
Mp |
About 213 °C, with decomposition. |
|
|
Identification |
IR |
Correspond with CRS |
|
|
Thin-layer chromatography |
Correspond with working standard |
|
|
C |
Correspond with working standard |
|
|
D |
Gives reaction of chlorides |
|
Appearance of solution S |
Clear and colorless |
|
|
pH |
4.3 to 5.3 |
|
|
Specific optical rotation |
+115 to +120 |
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|
Related substances |
Total impurities |
Not more than 0.3% |
|
|
Disregard limit |
0.025 times the area of the principal peak in the chromatogram obtained with reference solution |
|
Heavy metals |
Maximum 10ppm |
|
|
Loss on drying |
Maximum 0.5% |
|
|
Sulphated ash |
Maximum 0.1% |
|
|
Content |
98.5 per cent to 101.0 per cent (dried substance). |
|