China (Mainland)
Domperidone CAS NO.57808-66-9
- Min.Order: 10 Gram
- Payment Terms: L/C,D/A,D/P,T/T,
- Product Details
Keywords
- 57808-66-9
- Domperidone
- Motilium
Quick Details
- ProName: Domperidone
- CasNo: 57808-66-9
- Molecular Formula: C22H24ClN5O2
- Appearance: white or almost white powder
- Application: Peripheral dopamine receptor antagonis...
- DeliveryTime: within 7 days after order confirmation
- PackAge: 1kg/package, 25kg/bag, 25kg/drum
- Port: Shanghai, Qingdao, Tianjin, Ningbo, Xi...
- ProductionCapacity: 30 Kilogram/Month
- Purity: 99%+
- Storage: protected from light
- Transportation: By air, by courier, by sea
- LimitNum: 10 Gram
- Residue on Ignition: Maximum 0.1%
- Heavy Metal: Maximum 20ppm
- Valid Period: 2 years
Superiority
XI'AN VEDA CHEMICAL CO.,LTD(VEDACHEM), is specializes in APIs and Intermediates.
Domperidone is one of the main products in VEDACHEM.
Domperidone (INN, USAN, BAN, JAN) (brand name Motilium, many
others) is a drug developed by Janssen Pharmaceutica that acts as
a peripherallyselective antagonist of the dopamine D2 and D3 receptors.
It is administered orally, rectally, or intravenously. Domperidone is used
to relievenausea and vomiting; to increase the transit of food through
the stomach (that is, as a prokinetic agent via
increasing gastrointestinal peristalsis); and to promote lactation (breast
milk production) by release of prolactin. It is also used in scientific
research to study the biological function of dopamine, an
important neurotransmitter and hormone, in the body.
Domperidone is available in the form of tablets, orally disintegrating
tablets (based on Zydis technology), suspension and suppositories.
We can supply Domperidone in sample grade or medicine grade.
Please contact us for detailed information, such as COA/MSDS/MOA, etc.
Details
|
product Name |
Domperidone |
|
Synonyms |
alpha-[2-(diisopropylamino) ethyl]-alpha-phenyl-2-pyridineacetamide; Motilium |
|
Molecular Formula |
C22H24ClN5O2 |
|
Molecular Weight |
425.92 |
|
InChI |
InChI=1/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) |
|
CAS Registry Number |
57808-66-9 |
|
EINECS |
260-968-7 |
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Molecular Structure |
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Hazard Symbols |
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|
Risk Codes |
R62:; |
|
Safety Description |
S26:; |
Xn:Harmful;
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Appearance
|
White or almost white powder |
||
|
Solubility |
Practically insoluble in water, soluble in dimethylformamide, slightly soluble in ethanol (96 per cent) and in methanol. |
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|
Identification |
Melting point |
244℃ to 248℃ |
|
|
IR |
Correspond with CRS |
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|
Thin-layer chromatography |
Gives reaction of non-nitrogen substituted barbiturates |
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|
Appearance of solution |
Clear and not more intensely coloured than reference solution Y6 |
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Related substances |
Impurity A: |
Not more than 0.25% |
|
|
Impurity B: |
Not more than 0.25% |
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Impurity C: |
Not more than 0.25% |
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Impurity D: |
Not more than 0.25% |
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Impurity E: |
Not more than 0.25% |
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Impurity F: |
Not more than 0.25% |
||
|
Total impurities |
Not more than 0.5% |
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Disregard limit |
Not more than 0.05% |
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|
Heavy metals |
Maximum 20ppm |
||
|
Loss on drying |
Maximum 0.5% |
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Sulphated ash |
Maximum 0.1% |
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Storage |
Protected from light |
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Domperidone API
Domperidone Drug
Domperidone function
