China (Mainland)
Lomustine /cas:13010-47-4 CAS NO.13010-47-4
- Min.Order: 0 Metric Ton
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Product Details
Keywords
- treating brain tumors
- belustine
- Api-lomustine
Quick Details
- ProName: Lomustine /cas:13010-47-4
- CasNo: 13010-47-4
- Molecular Formula: C9H16ClN3O2
- Appearance: yellow powder.
- Application: Lomustine is an alkylating nitrosourea...
- DeliveryTime: 1-30days Depend on Quantity
- PackAge: lastic bucket，25kg/package，200KG/packa...
- Port: any port in China
- ProductionCapacity: 3 Metric Ton/Month
- Purity: ≥98%
- Storage: Store in a tightly closed container
- Transportation: by air/sea
- LimitNum: 0 Metric Ton
- Molecula weight: 233.6952
- Assay: ≥98%
- Appearance: yellow powder.
- Standard: BP
- Delivery Time: 1-30days Depend on Quantity
- payment terms: T/T in advance,etc.
Superiority
Superiority:
Aopharm is specialized in APIs, pharmaceutical intermediates & fine chemicals.
1. The best quality, competitive price.
2. The best service before or after shipment.
3. Rich experience in export operation.
4. Rich experience in modes of transportation.
5. Professional sale staff with chemical knowledge.
6. Full protecting of our customers’ profit.
Details
|
Formula |
C9H16CIN3O2 |
|
Molecular weight |
233.70 |
|
EINECS |
235-859-2 |
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CAS RN |
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CAS Name |
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Synonyms: |
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea; (chloro-2-ethyl)-1-cyclohexyl-3-nitrosourea; (cloro-2-etil)-1-cicloesil-3-nitrosourea; 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosoure; 1-(2-chloroethyl)-3-cyclohexyl-1-nitroso-ure; belustine; cecenu; ceenu; chloroethylcyclohexylnitrosourea; cinu; cyclohexylchloroethylnitrosourea; icig1109; n-(2-chloroethyl)-n’-cyclohexyl-n-nitroso-ure; nci-c04740; nsc79037; nsc-79037; rb1509; 1-chloro-3-cyclohexyl-1-ethyl-3-nitrosourea |
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Minimum assay |
≥98% |
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Form |
yellow powder |
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Solubility |
Soluble in ethanol (47 mg/ml at 25 °C), chloroform, water (<1 mg/ml at 25 °C), DMSO (47 mg/ml at 25 °C), and acetone. |
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Application |
Lomustine is clinically used to treat various forms of cancer. |
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Usage |
a highly lipid soluble drug, treating brain tumors |
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Melting point ca. |
88-90 ºC |
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Boiling point ca. |
354.07 °C |
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Density g/cm3 (20°C) |
1.31g/cm3 |
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Refractive index |
1.57 |
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Flash point |
133.2°C |
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Stability |
Stable under recommended storage conditions |
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Percent Composition |
C 46.25%, H 6.90%, Cl 15.17%, N 17.98%, O 13.69% |
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Packaging |
required by customer |
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Delivery Time |
overnight (USA/Canada); 3-5 days (worldwide) |
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Storage |
Store at 4° C |
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Transport information |
by air/sea |
Description
Lomustine is an alkylating nitrosourea compound that possesses antitumor activity similar to Carmustine (sc-204671) causing
DNA interstrand cross-linking. The compound is also a documented inhibitor of glutathione reductase, DLD(lipoamide dehydrogenase) and trypanothione reductase. Lomustine is a highly lipid soluble compound thus enabling it to cross the blood
brain barrier and rapidly disperse in tissue. In A2870 cells, Lomustine has been shown to induce p53 expression.