Lomustine; CCNU CAS NO.13010-47-4

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CCNU is the trade name for lomustine. CeeNU is another name for lomustine.

In some cases, health care professionals may use the trade name CCNU or other

names CeeNu when referring to the generic drug name lomustine.

Lomustine is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This

medication is classified as an "alkylating agent."

The application of Lomustine

· Treatment of brain tumors, both primary (developed in the brain) and metastatic (spread from another source).

· Hodgkin's disease and non-Hodgkin's lymphoma.

· Also has been used in treatment of melanoma, lung and colon cancer

Formula	C9H16CIN3O2
Molecular weight	233.70
EINECS	235-859-2
CAS RN	13010-47-4
CAS Name
Synonyms:	1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea; (chloro-2-ethyl)-1-cyclohexyl-3-nitrosourea; (cloro-2-etil)-1-cicloesil-3-nitrosourea; 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosoure; 1-(2-chloroethyl)-3-cyclohexyl-1-nitroso-ure; belustine; cecenu; ceenu; chloroethylcyclohexylnitrosourea; cinu; cyclohexylchloroethylnitrosourea; icig1109; n-(2-chloroethyl)-n’-cyclohexyl-n-nitroso-ure; nci-c04740; nsc79037; nsc-79037; rb1509; 1-chloro-3-cyclohexyl-1-ethyl-3-nitrosourea
Minimum assay	≥98%
Minimum stability
Form	yellow powder
Solubility	Soluble in ethanol (47 mg/ml at 25 °C), chloroform, water (<1 mg/ml at 25 °C), DMSO (47 mg/ml at 25 °C), and acetone.
Application
Usage	a highly lipid soluble drug, treating brain tumors
Melting point ca.	88-90 ºC
Boiling point ca.	354.07 °C
Density g/cm3 (20°C)	1.31g/cm3
Refractive index	1.57
Flash point	133.2°C
Stability	Stable under recommended storage conditions
Percent Composition	C 46.25%, H 6.90%, Cl 15.17%, N 17.98%, O 13.69%
Packaging	required by customer
Delivery Time	overnight (USA/Canada); 3-5 days (worldwide)
Storage	Store at 4° C
Transport information